Analysis of Semi-Volatile Organic Compounds by Shimadzu GCMSMS with Reduced Methylene Chloride UsageInnovative Solutions for Reducing Methylene Chloride
Oral Presentation
Prepared by J. Mitchell1, W. Lipps2, B. Mock1
1 - Pace Analytical Services, 12065 LEBANON ROAD, Mt. Juliet, TN, 37122, United States
2 - Shimadzu Scientific Insruments, Inc., 7102 Riverwood Drive, Columbia, MD, 21046, United States
Contact Information: [email protected]; 615-944-9517
ABSTRACT
EPA announced July 2024 a rule regarding the reduction or elimination of Methylene Chloride from most commercial applications. Historical environmental methods for the analysis of extractable organic compounds have called for volumes of sample from 100 ml to 1000 ml with extraction using up to 360 ml of methylene chloride. Due to growing concern and pending rules limiting that usage, Pace Analytical has developed a procedure combining multiple extractable methods into a single GCMSMS analysis. This method significantly reduces the use of methylene chloride while providing robust analytical processes that meet or exceed existing requirements. This discussion will provide a comparison of multiple extraction procedures using minimal amounts of methylene chloride or alternative solvents for a single GCMSMS analysis of a combined extractable organics and pesticide target analyte list. The data presented will compare multiple extraction procedures designed to reduce or eliminate methylene chloride usage while delivering equivalent or lower limits of detection and method precision and accuracy. Samples were extracted using separatory funnel or micro extraction methods and analyzed on a Shimadzu GCMS-TQ8050 NX Triple Quadrupole GCMS. All results presented are compared to existing criteria documented in the historically published methods.
