From EPA 1633 to 1633A: the Evolution of PFAS in Solids Testing by Automated Solvent Extraction Coupled with Reliable LC-MS/MS.Per- and Polyfluoroalkyl Substances (PFAS) in the Environment
Oral Presentation
Prepared by R. Marfil-Vega1, B. Liu2, L. Abu-Al-Halaweh2, A. Stell2, O. Shrestha1, T. Matsubara1
1 - Shimadzu Scientific Instruments, 10330 Old Columbia Rd, Columbia, MD, 21046, United States
2 - CEM Corporation, , , United States
Contact Information: [email protected]; 410-910-0884
ABSTRACT
In this work we evaluated the performance of an automated solvent extraction system coupled with a robust and reliable LC-MS/MS for PFAS analysis in diverse solids samples according to EPA 1633A. This effort is a continuation of the project presented during NEMC 2024 with the focus on the analysis of Ottawa sand by EPA 1633. In addition to expanding the diversity of samples to be analyzed, to include contaminated soil and tissue, we analyzed the extracts with a novel LC-MS probe developed to yield better heat distribution and more consistent nebulization for improved sensitivity and reproducibility, essential parameters for routine testing of PFAS in challenging environmental matrices. The CEM EDGE PFAS system was used for the extraction of the samples in a series of experiments to assess background PFAS, extraction recovery, method detection limits, and robustness among others. Extracts were subsequently cleaned-up as described in EPA 1633A. Samples were then analyzed and data processed using the Shimadzu LCMS-8060RX and LabSolutions Insight. In this presentation we will share the outcomes from the performance evaluation of the workflow described above for the analysis of contaminated soils and tissue samples.
